A Biomarker Panel of Radiation-Upregulated miRNA as Signature for Ionizing Radiation Exposure
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چکیده
منابع مشابه
Effect of Exposure to Ionizing Radiation on Biomarker of Oxidative Damage of DNA
Introduction: one of the most important complications of exposure to ionizing radiation is emergence of cancer tumors, which happens as a result of oxidative DNA. Therefore, the present study was conducted, aimed to measuring 8-DIHYDROxy- 2’- DEOXYGUANOSINE (8-OHdG) level in radiographers’ urine as oxidative damage biomarker, as well as comparing this biomarker with cumulative effective doses....
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BACKGROUND There is increasing evidence to suggest that miRNAs play an important role in predicting cancer survival. To identify a panel of miRNA signature that can divided tumor from normal bladder using miRNA expression levels, and to assess the prognostic value of this specific miRNA markers in bladder cancer (BCa). METHODS A comprehensive meta-review of published miRNA expression profiles...
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متن کاملPredicting ionizing radiation exposure using
Gene signatures derived from transcriptomic data using machine Background: learning methods have shown promise for biodosimetry testing. These signatures may not be sufficiently robust for large scale testing, as their performance has not been adequately validated on external, independent datasets. The present study develops human and murine signatures with biochemically-inspired machine learni...
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ژورنال
عنوان ژورنال: Life
سال: 2020
ISSN: 2075-1729
DOI: 10.3390/life10120361